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ICU Scores: Sequential Organ Failure Assessment (SOFA)

During the past 20 years, ICU risk-prediction models have undergone significant development, validation, and refinement. Among the general ICU severity of illness scoring systems, the Acute Physiology and Chronic Health Evaluation (APACHE), Mortality Prediction Model (MPM), and the Simplified Acute Physiology Score (SAPS) have become the most accepted and used. To risk-adjust patients with longer, more severe illnesses like sepsis and acute respiratory distress syndrome, several models of organ dysfunction or failure have become available, including the Multiple Organ Dysfunction Score (MODS), the Sequential Organ Failure Assessment (SOFA), and the Logistic Organ Dysfunction Score (LODS).

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine.
Intensive Care Med. 1996 Jul;22(7):707-10.
Vincent JL, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, Reinhart CK, Suter PM, Thijs LG

Sequential Organ Failure Assessment (SOFA)
Select Unit
std
SI
Cardiovascular
Respiratory
Systolic Blood Pressure
PaO2
Diastolic Blood Pressure
FIO2 as percentage (%)
Dopamine dose (µg/kg/min)
Neuro
Epinephrine dose (µg/kg/min)
Glasgow coma score (calculate)
Norepinephrine dose (µg/kg/min)
Coagulation
Dobutamine dose (µg/kgmin)
Platelet count per µL (X1000)
Liver
Renal
Serum bilirubin
Serum creatinine
Urine output in mL per day
SOFA Score
Organ Scores
Cardiovascular
Respiratory
Coagulation
Renal
Neuro
Liver

Glascow Coma Score

Eyes Opening

Verbal Response

Motor Response

spontaneous
to speech
to pain
absent

converses & oriented
converses & dsoriented
iappropriate
incomprehensible
absent

obeys
localizes pain
withdraws (flexion)
decorticate (flexion) rigidity
decerebrate (extension) rigidity
absent

Glasgow Coma Score=

Up to SOFA

ICU Scores APACHE II SAPS II MPM-0 MPM-24 MPM-48 MPM-Over Time SOFA MODS PRISM

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